Villain is unknown but I assume he's some kind of a reg (although his sizing is strange).
This is the spot I find myself struggling much. I would like to ask you about default strategy here. I often get barreled away in that kind of a spots and I wonder if I should only play for a setmine here.

So first PF: My understanding is that if I call here medium pocket pair like 88 I don't do it only for a set, right? 88 has some limited ability to flop overpair and/or have some kind of SDV . If I had hand like 22-66 should I fold because even if I flop a set it will be hard to get value OOP?

PostFlop: How many streets we can call on a low dry structure like this? Do villain cbets that kind of a board often with some two overs or he is weighted towards better overpairs/sets? Can I ever count that he will cbet flop eventually turn and give up by checkbacking?