GTO consept

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GTO consept

Hi, i need help to understand a consept. Say on the river when our opponent bets pot, im getting 2-1 odds and have to win the pot 33% of the time. BUT our opponent needs to be succesful 50% of the time. When i read about GTO the theory says i should defend with 50% of my range here. When i analyze theese riverspots, should i count out my top 50% or 33% of combos to call with?

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