Villian is a agro fish, I have seen him bet 100 into a 75 dollar pot then 200 on the turn and fold for 160 more when he got raised.  I have also seen him call off 150bb with just a ace 4 kicker to what was obviously a better hand.  on a very straight coordinated board.  

we are playing 2-5 full ring

Villian  900

hero 820

other players not so important

Villain opens for 35 utg +3,  one flat, hero flats on button with 88.  

Flop 2d 2s 4d

villian bets 150, fold, hero calls

Turn is a 5h

villian bets 300, hero ?

call raise or fold?  If I call turn, hero leaves himself with 335 on the river.