Should I call preflop small Pocker Pairs from the BB vs UTG-CO opens?

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Should I call preflop small Pocker Pairs from the BB vs UTG-CO opens?

Sizing of open is 3x. The ability to extract value when hitting our sets is not as good now because we're out of position. The fact that our hand is bad to continue with vs aggression when we miss is also much worse now that we're oop. So, what should I do with 66-22? Is it worth to call?

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