V is like 65/0!/0 over 35 hands.

flop : Def range bet vs this player. Yes he could have 8x sometimes but he would also check call with tons of low equity hand even vs half pot size.

turn : Gotcha :) Bet or Check? Check back would be def one of the option vs Reg.

What factors should be considered to determine the best exploitative action?

1. I am blocking his Qx heavily. And I have Qh.
2. He could have T9o on this spot? Yes prob nearly 100% combos.
3. What kind of hand would he defend with vs normal 75% bet? Wouldn't be surprised if he check call with naked FD or low pp.
4. How much will he bluff otr after check/check ott? Ummm not sure, he would have tons of trash otr, tho. But if he doesn't bluff otr at all, my check back would be poor option.
5. He would be inerastic with decent hands(trips+?) vs big bet/big raise otr? Probably yes, I think.

river : Faced overbet from villain, sizing? After check back ott, raise jam is the only sizing for me. Im blocking his TP heavily, so his over betting range would be fairly polarized here. And I think his value range would be inerastic vs my jam as mentioned above.
At the time ott, I thought that I wanna let him see river card and if he hit some straight or flush even on 4card straight/flush board, he would stickily defend my big bet/raise.

What line/sizing would you guys take ott and otr?

Any comments are welcome. Thanks :)