The Computer Poker Research Group at the University of Alberta has finally cracked heads-up limit Hold'em and published their GTO solution to the game. They have published their solution in the January issue of Science, one of the highest ranked scientific journals. Their research has sparked quite an interest in the media and on (obviously) 2+2.
Link to article (need Science subscription to read): Heads-up limit hold’em poker is solved
Here are a couple of summaries for us simple folks:
You can play their GTO HU Limit Hold'em bot "Cepheus" here (a lot of traffic currently, so can be slow):
Here you can also explore the full GTO strategy for preflop and postflop play. In practice, HU limit Hold'em has been dead for a long time as a money-making game, but now it's officially gone. I'm not totally sure how I feel about that, but I am enthusiastic about the research as such. It's fun, and can teach us something about other poker games (which are vastly more complicated).
It's becoming very clear that we can not afford to be lazy in this day and age. Study hard and keep up, or you will be left behind. Or you can (as I plan to do soon) add live play to the menu. I doubt GTO strategies will find their way into casinos. :-)