5-handed 2/4 NL. Effective stacks is $1300 Villain opens to 12. Hero calls CO with

Pot is 30. Flop is 664 rainbow. Villain continues for 18. Hero raises to 48.

Rationale on flop decision: We want to protect our equity from hands that have two to our pair over cards and there's around 22 bad turn cards for us (6 ranks * 4 cards) - 2 cards in villains hands. We also should have more 6s than villain so it's difficult for him to 3bet bluff us and if called we preserve optionality to either turn our hand into a bluff or to try and get to showdown as cheaply as possible.

What are peoples thoughts?