I have a more general question, how do you play these kind of hands? When do you give up? In all situations, so as 3-bettor, caller, ip, oop, etc. Just two examples what I mean:

Hand 1

BTN: 104.6 BB
SB: 153 BB
BB: 87.2 BB
UTG: 101.6 BB
Hero (MP): 104.6 BB
CO: 109.4 BB

SB posts SB 0.4 BB, BB posts BB 1 BB

Pre Flop: (pot: 1.4 BB) Hero has Qs Js
fold, Hero raises to 2.4 BB, CO raises to 8.4 BB, fold, fold, fold, Hero calls 6 BB

Is it a fold preflop given our positions? How would you play if it was CO vs BTN?

Flop : (18.2 BB, 2 players) 3h 7c Qc
Hero checks, CO bets 5.8 BB, Hero calls 5.8 BB

Turn : (29.8 BB, 2 players) 3d
Hero checks, CO bets 22 BB, Hero calls 22 BB

Fold vs this sizing?

River : (73.8 BB, 2 players) 4h
Hero checks, CO bets 73.2 BB and is all-in, Hero

Hand 2

BTN: 103.2 BB
SB: 133 BB
Hero (BB): 129.6 BB
UTG: 131.6 BB
MP: 105 BB
CO: 82 BB

SB posts SB 0.4 BB, Hero posts BB 1 BB

Pre Flop: (pot: 1.4 BB) Hero has Jc Ac
fold, MP raises to 3 BB, CO calls 3 BB, BTN calls 3 BB, fold, Hero raises to 16 BB, MP calls 13 BB, fold, fold

Flop : (38.4 BB, 2 players) As 9d 6s
Hero bets 12.8 BB, MP calls 12.8 BB

Turn : (64 BB, 2 players) 4c
Hero checks, MP bets 20.2 BB, Hero calls 20.2 BB

It feels kind of commited at this point with SPR around 1.

River : (104.4 BB, 2 players) 5h
Hero checks, MP bets 56 BB and is all-in, Hero